On line a recent scientific publication regarding the Biphasic malignant pleural mesothelioma (MPM).
This research is aimed at the study of the estrogen receptor beta ( ERβ ) and, in particular, to its induction mediated by intracellular lactate at the level of cells of biphasic MPM.
In fact, researchers have shown that the concentration of intracellular lactate induces the expression of Erβ
Through experimental studies, it has been proved that the treatment with the agonist ERβ leads to reduced cell proliferation and could , therefore , function as potential antitumor.
The selective action of the agonist could , therefore , represent a new effective strategy for the MPM treatment.